Blood-brain barrier amenable gold nanoparticles biofabrication in aged cell culture medium
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چکیده
منابع مشابه
A cell culture model of the blood-brain barrier
The actions of an intracellular nitric oxide generator compound on the properties of a co-culture model of the blood-brain barrier are described. Addition of the iron-sulphur cluster nitrosyl Roussin's black salt (RBS, heptanitrosyl-tri-mu3-thioxotetraferrate (1-)) resulted in a rapid and dose-dependent (50-250 microM) decline in the electrical resistance displayed by co-cultures of vascular en...
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BACKGROUND The blood brain barrier (BBB) controls the brain microenvironment and limits penetration of the central nervous system (CNS) by chemicals, thus creating an obstacle to many medical imaging and treatment procedures. Research efforts to identify viable routes of BBB penetration have focused on structures such as micelles, polymeric nanoparticles and liposomes as drug carriers, however,...
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ژورنال
عنوان ژورنال: Materials Today Bio
سال: 2020
ISSN: 2590-0064
DOI: 10.1016/j.mtbio.2020.100072